melitensis vaccineCenter for Food Security and Public Health, Iowa State University, 2012 Transmission in HumansContact with infected animal tissuesPlacenta, fetus, fetal fluids, vaginal dischargesConsumption of unpasteurized dairy productsLaboratory-acquiredAccidental injectionRev-1 B. History of BrucellosisAlice EvansAmerican bacteriologist credited with linking the organisms in the 1920sDiscovered similar morphology and pathology between:Bangs Bacterium abortus Bruces Micrococcus melitensisBrucella nomenclatureCredited to Sir David BruceCenter for Food Security and Public Health, Iowa State University, 2012 History of BrucellosisBernhard Bang (1848-1932)Danish physician and veterinarian Discovered Bacterium abortus could infect cattle, horses, sheep, and goats The Wellcome Trust, Illustrated History of Tropical Diseases History of BrucellosisSir David Bruce (1855-1931)British Army physician and microbiologist Discovered Micrococcus melitensisĬenter for Food Security and Public Health, Iowa State University, 2012Professor FEG Cox. History of BrucellosisJeffery Allen MarstonBritish Army surgeonContracted Malta feverDescribed his own case in great detail History of BrucellosisSir William Burnett (1779-1861)Physician General to the British NavyDifferentiated among the various fevers affecting soldiers Human Populations at RiskOccupational diseaseLaboratory workersFarmersVeterinariansConsumers of unpasteurized dairy productsVaccine-exposedCenter for Food Security and Public Health, Iowa State University, 2012 Species AffectedMainly sheep and goatsOccasionall圜attle, camels, dogsRarely Horses, pigsHumans are very susceptibleCenter for Food Security and Public Health, Iowa State University, 2012 Geographic DistributionMediterranean region, Middle EastCentral AmericaSporadic cases in other countriesCenter for Food Security and Public Health, Iowa State University, 2012 The Many Names of BrucellosisHuman DiseaseMalta FeverUndulant FeverMediterranean FeverRock Fever of GibraltarGastric FeverAnimal DiseaseBangs DiseaseEnzootic AbortionEpizootic AbortionSlinking of CalvesRam EpididymitisContagious AbortionCenter for Food Security and Public Health, Iowa State University, 2012 The OrganismBrucella melitensisGram negative coccobacillusFacultative intracellular pathogenThree biovarsAll cause disease in small ruminantsGeographic distribution variesCan persist in environmentCenter for Food Security and Public Health, Iowa State University, 2012 OverviewOrganismHistoryEpidemiologyTransmissionDisease in HumansDisease in AnimalsPrevention and ControlActions to TakeCenter for Food Security and Public Health, Iowa State University, 2012 Ovine and Caprine Brucellosis:Brucella melitensisUndulant Fever,Malta Fever,Mediterranean Fever,Contagious AbortionĬenter for Food Security and Public Health, Iowa State University, 2012

Brucellose caprine